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ITK antibody

ITK Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 5G6 unconjugated
Catalog No. ABIN969222
  • Target See all ITK Antibodies
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Reactivity
    • 48
    • 19
    • 12
    • 6
    • 3
    Human
    Host
    • 62
    • 3
    • 2
    Mouse
    Clonality
    • 64
    • 3
    Monoclonal
    Conjugate
    • 28
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITK antibody is un-conjugated
    Application
    • 39
    • 35
    • 14
    • 14
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purpose
    ITK Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human ITK expressed in E. Coli.
    Clone
    5G6
    Isotype
    IgG1
    Top Product
    Discover our top product ITK Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

    Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).

  • Target
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Alternative Name
    ITK (ITK Products)
    Synonyms
    Emt antibody, Tcsk antibody, Tsk antibody, EMT antibody, LPFS1 antibody, LYK antibody, PSCTK2 antibody, IL2 inducible T cell kinase antibody, IL2 inducible T-cell kinase antibody, IL2-inducible T-cell kinase antibody, Itk antibody, ITK antibody
    Background

    Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    Aliases: EMT, LYK, PSCTK2, MGC126257, MGC126258

    Molecular Weight
    72kDa
    Gene ID
    3702
    HGNC
    3702
    UniProt
    Q08881
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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