IL-34 antibody

Catalog No. ABIN969216

Product Details anti-IL-34 Antibody

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-34 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: IL34 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human IL34 expressed in E. Coli.

Clone: 1D12

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-IL-34 antibody (ABIN969216)

Slomiany, Baker, Elliott, Grossel: "Changes in motility, gene expression and actin dynamics: Cdk6-induced cytoskeletal changes associated with differentiation in mouse astrocytes." in: Journal of cellular biochemistry, Vol. 99, Issue 2, pp. 635-46, (2006) (PubMed).

Target Details for IL-34

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Alternative Name: IL34 (IL34 Products)

Synonyms: C16orf77 antibody, IL-34 antibody, 2010004A03Rik antibody, AI593503 antibody, C18H16ORF77 antibody, interleukin 34 antibody, IL34 antibody, Il34 antibody

Background:

Description: Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.Tissue specificity: Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

Aliases: IL-34, C16orf77, MGC34647, IL34

Molecular Weight: 27.5kDa

Gene ID: 146433

HGNC: 146433

UniProt: Q6ZMJ4

Pathways: RTK Signaling