HPS1 antibody

Catalog No. ABIN969198

Product Details anti-HPS1 Antibody

Target: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPS1 antibody is un-conjugated

Application: ELISA

Purpose: HPS1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of HPS1 expressed in E. Coli.

Clone: 5G12G2

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HPS1 antibody (ABIN969198)

Crowell, Gill: "Medical screening and evacuation: cauda equina syndrome in a combat zone." in: The Journal of orthopaedic and sports physical therapy, Vol. 39, Issue 7, pp. 541-9, (2009) (PubMed).

Fréchette, Leit, Woo, Lapointe, Jeannotte, Moradei, Paquin, Bouchain, Raeppel, Gaudette, Zhou, Vaisburg, Fournel, Yan, Trachy-Bourget, Kalita, Robert, Lu, Rahil, Robert Macleod, Besterman, Li, Delorme: "4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors." in: Bioorganic & medicinal chemistry letters, Vol. 18, Issue 4, pp. 1502-6, (2008) (PubMed).

Huizing, Parkes, Helip-Wooley, White, Gahl: "Platelet alpha granules in BLOC-2 and BLOC-3 subtypes of Hermansky-Pudlak syndrome." in: Platelets, Vol. 18, Issue 2, pp. 150-7, (2007) (PubMed).

Kobashi, Yoshida, Miyashita, Niki, Matsushima: "Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene." in: Internal medicine (Tokyo, Japan), Vol. 44, Issue 6, pp. 616-21, (2005) (PubMed).

Nazarian, Falcón-Pérez, DellAngelica: "Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8770-5, (2003) (PubMed).

Target Details for HPS1

Target: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Alternative Name: HPS1 (HPS1 Products)

Synonyms: HPS antibody, HPS1 antibody, MGC123240 antibody, im:7143944 antibody, zgc:123240 antibody, 6030422N11Rik antibody, BB405864 antibody, Hps antibody, ep antibody, HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 antibody, Hermansky-Pudlak syndrome 1 antibody, HPS1 antibody, hps1 antibody, Hps1 antibody

Background:

Description: Hermansky-Pudlak syndrome 1. This protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene, the full-length sequences of some of these have not been determined yet.

Aliases: HPS, MGC5277, HPS1

Gene ID: 3257

HGNC: 3257

UniProt: Q92902