HPRT1 antibody

Catalog No. ABIN969197

Product Details anti-HPRT1 Antibody

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPRT1 antibody is un-conjugated

Application: ELISA

Purpose: HPRT Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of HPRT expressed in E. Coli.

Clone: 1F8D11

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HPRT1 antibody (ABIN969197)

Manjanatha, Shelton, Bishop, Shaddock, Dobrovolsky, Heflich, Webb, Blankenship, Beland, Greenlees, Culp: "Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green." in: Mutation research, Vol. 547, Issue 1-2, pp. 5-18, (2004) (PubMed).

Target Details for HPRT1

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Alternative Name: HPRT (HPRT1 Products)

Synonyms: HGPRT antibody, HPRT antibody, C81579 antibody, HPGRT antibody, Hprt1 antibody, Hgprtase antibody, Hprt antibody, id:ibd1344 antibody, id:ibd5108 antibody, wu:fc10g09 antibody, zgc:56221 antibody, zgc:86608 antibody, hgprt antibody, hprt antibody, prtfdc1 antibody, hprt1 antibody, hprt1l antibody, zgc:55561 antibody, zgc:86771 antibody, hypoxanthine phosphoribosyltransferase 1 antibody, hypoxanthine guanine phosphoribosyl transferase antibody, hypoxanthine phosphoribosyltransferase 1 L homeolog antibody, phosphoribosyl transferase domain containing 1 antibody, HPRT1 antibody, Hprt antibody, Hprt1 antibody, hprt1 antibody, hprt1.L antibody, prtfdc1 antibody

Background: The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy . This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.

UniProt: P00492

Pathways: Ribonucleoside Biosynthetic Process