GATA1 antibody

Catalog No. ABIN969166

Product Details anti-GATA1 Antibody

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GATA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: GATA1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human GATA1 expressed in E. Coli.

Clone: 4F5

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-GATA1 antibody (ABIN969166)

Wierenga, Vellenga, Schuringa: "Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation." in: Blood, Vol. 115, Issue 22, pp. 4367-76, (2010) (PubMed).

Blackford, Parmigiani, Kensler, Wolfgang, Jones, Zhang, Parsons, Lin, Leary, Eshleman, Goggins, Jaffee, Iacobuzio-Donahue, Maitra, Klein, Cameron, Olino, Schulick, Winter, Vogelstein, Velculescu, Kinzler, Hruban: "Genetic mutations associated with cigarette smoking in pancreatic cancer." in: Cancer research, Vol. 69, Issue 8, pp. 3681-8, (2009) (PubMed).

Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

Target Details for GATA1

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Alternative Name: GATA1 (GATA1 Products)

Synonyms: ERYF1 antibody, GATA-1 antibody, GF-1 antibody, GF1 antibody, NF-E1 antibody, NFE1 antibody, XLANP antibody, XLTDA antibody, XLTT antibody, Gata-1 antibody, Gf-1 antibody, eryf1 antibody, Eryf1 antibody, GATA1 antibody, gata-1 antibody, Gata1 antibody, si:dkeyp-77f7.5 antibody, gata1 antibody, gata1a-A antibody, xGATA-1 antibody, xgata1 antibody, XGATA-1B antibody, gata1b-A antibody, gta1 antibody, zg1 antibody, NF-E1a antibody, GATA binding protein 1 antibody, GATA binding protein 1 (globin transcription factor 1) antibody, amidase antibody, aspartyl/glutamyl-tRNA amidotransferase subunit A antibody, putative amidase antibody, GatA1 antibody, glutamyl-tRNA amidotransferase subunit A antibody, hematopietic transcription factor GATA-1 antibody, GATA binding protein 1b antibody, GATA binding protein 1 L homeolog antibody, GATA binding protein 1 S homeolog antibody, GATA binding protein 1a antibody, erythroid transcription factor antibody, GATA1 antibody, Gata1 antibody, gatA1 antibody, gata-1 antibody, gata1b antibody, gata1.L antibody, gata1.S antibody, gata1a antibody, LOC108348091 antibody

Background:

Description: erythroid specific transcription factor,GATA sequence binding protein (same as EryF1,NF-E1,EF-1,EF gamma-a,GF1),expressed in RBC,mast cell,megakaryocyte,hematopoietic progenitor cell,testis,associated with a special class of nuclear bodies,activated by erythropoietin,inactivated by coactivation of DEATH receptors (TNFRSF6) mediated caspase cleavage Tissue specificity: Erythrocytes

Aliases: GF1, GF-1, NFE1, XLTT, ERYF1, GATA-1, GATA1

Molecular Weight: 42.7kDa

Gene ID: 2623

HGNC: 2623

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin