c-FOS antibody
-
- Target See all c-FOS (c-Fos) Antibodies
- c-FOS (c-Fos) (c-Fos)
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This c-FOS antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- FOS Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human FOS expressed in E. Coli.
- Clone
- 2G2
- Isotype
- IgG1
-
-
- Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).
: "FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis." in: Cancer investigation, Vol. 27, Issue 8, pp. 816-24, (2009) (PubMed).
: "
-
c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).
-
- Target
- c-FOS (c-Fos) (c-Fos)
- Alternative Name
- FOS (c-Fos Products)
- Synonyms
- AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
- Background
-
Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Aliases: p55, AP-1, C-FOS
- Molecular Weight
- 40.7kDa
- Gene ID
- 2353
- HGNC
- 2353
- UniProt
- P01100
- Pathways
- S100 Proteins
-