Fibronectin 1 antibody

Catalog No. ABIN969149

Product Details anti-Fibronectin 1 Antibody

Target: Fibronectin 1 (FN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibronectin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: FN1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human FN1 expressed in E. Coli.

Clone: 2F4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Fibronectin 1 antibody (ABIN969149)

Li, Li, Duan, Cai, You, Zhou, Yang, Tuo, Liu: "Blockage of TGF-α Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells." in: BioMed research international, Vol. 2019, pp. 8231267, (2019) (PubMed).

Guo, You, Li, Tuo, Liu: "Spherical silica nanoparticles promote malignant transformation of BEAS-2B cells by stromal cell-derived factor-1α (SDF-1α)." in: The Journal of international medical research, Vol. 47, Issue 3, pp. 1264-1278, (2019) (PubMed).

Ryschich, Khamidjanov, Kerkadze, Büchler, Zöller, Schmidt: "Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer." in: Pancreas, Vol. 38, Issue 7, pp. 804-10, (2009) (PubMed).

Huang, Zhang, Kim, Ge, Annis, Mosher, Greenspan: "Fibronectin binds and enhances the activity of bone morphogenetic protein 1." in: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25879-88, (2009) (PubMed).

Target Details for Fibronectin 1

Target: Fibronectin 1 (FN1)

Alternative Name: FN1 (FN1 Products)

Synonyms: FN1 antibody, FN antibody, cig antibody, fibronectin antibody, finc antibody, lets antibody, msf antibody, Fn antibody, fn2 antibody, fb80d10 antibody, wu:fb80d10 antibody, CIG antibody, ED-B antibody, FINC antibody, FNZ antibody, GFND antibody, GFND2 antibody, LETS antibody, MSF antibody, E330027I09 antibody, Fn-1 antibody, FIBNEC antibody, fn-1 antibody, fibronectin 1 antibody, fibronectin 1a antibody, fibronectin 1 S homeolog antibody, FN1 antibody, fn1 antibody, fn1a antibody, Fn1 antibody, fn1.S antibody

Background:

Description: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Aliases: FN, CIG, FNZ, MSF, ED-B, FINC, GFND, LETS, GFND2

Molecular Weight: 262.6kDa

Gene ID: 2335

HGNC: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy