Fibulin 5 antibody

Catalog No. ABIN969145

Product Details anti-Fibulin 5 Antibody

Target: Fibulin 5 (FBLN5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: ELISA

Purpose: Fibulin 5 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of Fibulin 5 expressed in E. Coli.

Clone: 3F8D5

Isotype: IgM

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Fibulin 5 antibody (ABIN969145)

Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

Lee, Roy, Mogford, Schiemann, Mustoe: "Fibulin-5 promotes wound healing in vivo." in: Journal of the American College of Surgeons, Vol. 199, Issue 3, pp. 403-10, (2004) (PubMed).

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: Fibulin 5 (FBLN5 Products)

Synonyms: zgc:103575 antibody, FBLN5 antibody, MGC108414 antibody, Fibulin-5 antibody, DKFZp469K0327 antibody, ADCL2 antibody, ARCL1A antibody, ARMD3 antibody, DANCE antibody, EVEC antibody, FIBL-5 antibody, UP50 antibody, A55 antibody, fibulin 5 antibody, fbln5 antibody, FBLN5 antibody, Fbln5 antibody

Background:

Description: Fibulin 5(FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Aliases: EVEC, UP50, ARMD3, DANCE

Gene ID: 10516

HGNC: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome