FGG antibody
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- Target See all FGG Antibodies
- FGG (Fibrinogen gamma Chain (FGG))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This FGG antibody is un-conjugated
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Application
- ELISA, Immunocytochemistry (ICC)
- Purpose
- FGG Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human FGG expressed in E. Coli.
- Clone
- 5A6
- Isotype
- IgG2b
- Top Product
- Discover our top product FGG Primary Antibody
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- Application Notes
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).
: "Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions." in: Biochemistry, Vol. 48, Issue 36, pp. 8656-63, (2009) (PubMed).
: "
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The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).
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- Target
- FGG (Fibrinogen gamma Chain (FGG))
- Alternative Name
- FGG (FGG Products)
- Background
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Description: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Aliases: FGG
- Molecular Weight
- 52kDa
- Gene ID
- 2266
- HGNC
- 2266
- UniProt
- P02679
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