FABP2 antibody

Catalog No. ABIN969124

Product Details anti-FABP2 Antibody

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FABP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: FABP2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human FABP2 expressed in E. Coli.

Clone: 9A9B7B3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-FABP2 antibody (ABIN969124)

Fisher, Li, Burwinkel, Kühr, Hoffmann, Möhlig, Spranger, Pfeiffer, Boeing, Schrezenmeir, Döring: "Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 38, Issue 5, pp. 341-5, (2006) (PubMed).

Kim, Yun, Byun, Yoo, Lee, Suh: "Codon 54 polymorphism of the fatty acid binding protein 2 gene is associated with increased fat oxidation and hyperinsulinemia, but not with intestinal fatty acid absorption in Korean men." in: Metabolism: clinical and experimental, Vol. 50, Issue 4, pp. 473-6, (2001) (PubMed).

Georgopoulos, Aras, Tsai: "Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes." in: The Journal of clinical endocrinology and metabolism, Vol. 85, Issue 9, pp. 3155-60, (2000) (PubMed).

Target Details for FABP2

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Alternative Name: FABP2 (FABP2 Products)

Synonyms: I-FABP antibody, ifabp antibody, zgc:92264 antibody, IFABP antibody, fabpi antibody, i-fabp antibody, fabp2-A antibody, FABP2 antibody, FABPI antibody, FABP antibody, Fabpi antibody, fabp2 antibody, fabp2a antibody, fatty acid binding protein 2, intestinal antibody, fatty acid binding protein 2 antibody, fatty acid binding protein 2 L homeolog antibody, fabp2 antibody, FABP2 antibody, Fabp2 antibody, fabp2.L antibody

Background:

Description:

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

Aliases: FABPI, I-FABP, MGC133132, FABP2

Molecular Weight: 15kDa

Gene ID: 2169

HGNC: 2169

UniProt: P12104