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KRT8 antibody (AA 391-483)

Name: KRT8 antibody (AA 391-483)
Brand: antibodies-online
SKU: ABIN969080
Price: 525.8 USD
Availability: InStock

KRT8 Reactivity: Human WB, IHC, ELISA, ICC Host: Mouse Monoclonal 8A5D12 unconjugated

Immunohistochemical analysis of paraffin-embedded human Kidney tissues using CK8 mouse mAb (KRT8 antibody (AA 391-483))

IHC

Confocal immunofluorescence analysis of methanol-fixed ECA109 cells (left) and HepG2 cells (right) using CK8 mouse mAb (green), showing cytoplasmic localization. (KRT8 antibody (AA 391-483))

Western blot analysis using CK8 mouse mAb against A549 (1), Hela (2), MCF-7 (3), A431 (4) and HepG2 (5) cell lysate. (KRT8 antibody (AA 391-483))

Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), lung cancer (B) and ovarian cancer tissue (C), showing membrane and cytoplasmic localization with DAB staining using CK8 mouse mAb. (KRT8 antibody (AA 391-483))

IHC

4 images

(1 reference)

Catalog No. ABIN969080

Datasheet as PDF

Target See all KRT8 Antibodies

KRT8 (Keratin 8 (KRT8))
Binding Specificity
23

16

13

13

11

8

6

6

5

5

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 391-483
Reactivity
265

86

82

33

33

31

30

16

14

10

8

5

4

3

2

1

1

1
Human
Host
148

125

3
Mouse
Compatible Secondaries
Clonality
146

128
Monoclonal
Conjugate
144

22

16

9

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1
This KRT8 antibody is un-conjugated
Application
170

100

98

81

66

49

41

40

29

29

24

17

5

5

4

4

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purpose

Cytokeratin 8 Antibody

Purification

Ascitic fluid

Immunogen

Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. Coli.

Clone

8A5D12

Isotype

IgG1

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KRT8 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

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KRT8 Reactivity: Human, Rat, Mouse WB, IF, IHC, ELISA, ICC Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) (Ser726), (Ser731) antibody
KRT8 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

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KRT8 Reactivity: Human, Rat, Zebrafish (Danio rerio) WB, IF, IHC, FACS, StM Host: Mouse Monoclonal H1 unconjugated

anti-Keratin 8 (KRT8) (AA 91-381) antibody
KRT8 Reactivity: Human, Rat, Monkey, Dog WB, IF, IHC, IHC (p) Host: Mouse Monoclonal 1B12 unconjugated

anti-Keratin 8 (KRT8) (AA 1-483) antibody
KRT8 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) antibody
KRT8 Reactivity: Human, Cow, Pig, Rabbit, Sheep IF, IHC, FACS, StM Host: Mouse Monoclonal B22-1 unconjugated

anti-Keratin 8 (KRT8) (N-Term) antibody
KRT8 Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Keratin 8 (KRT8) (Middle Region) antibody
KRT8 Reactivity: Human, Rat, Mouse, Cow, Pig, Rabbit, Dog, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

ELISA: 1/10000
ICC: 1/200 - 1/1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
Target

KRT8 (Keratin 8 (KRT8))

Alternative Name

Cytokeratin 8 (KRT8 Products)

Synonyms

CARD2 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, K2C8 antibody, K8 antibody, KO antibody, AA960620 antibody, AL022697 antibody, AU019895 antibody, Card2 antibody, EndoA antibody, Krt-2.8 antibody, Krt2-8 antibody, CYKER antibody, KRT2-8 antibody, KERATIN8 antibody, ck8 antibody, cyk8 antibody, k2c8 antibody, card2 antibody, krt2-5 antibody, MGC69490 antibody, KRT8 antibody, DreK8 antibody, cb186 antibody, krt2-8 antibody, sb:cb186 antibody, wu:fa20h05 antibody, wu:fa95h10 antibody, wu:fb96c06 antibody, zf-K8 antibody, zfk8 antibody, DKFZp468F2127 antibody, keratin 8 antibody, keratin 8 S homeolog antibody, KRT8 antibody, Krt8 antibody, krt8.S antibody, krt8 antibody

Background

Description: Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Aliases: CK8, CYK8, K2C8, KRT8

Molecular Weight

54kDa

Gene ID

3856

HGNC

3856

UniProt

P05787