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Cytokeratin 19 antibody (AA 80-400)

Name: Cytokeratin 19 antibody (AA 80-400)
Brand: antibodies-online
SKU: ABIN969076
Price: 467.5 USD
Availability: InStock

KRT19 Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 9H8G6 unconjugated

Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using KRT19 mouse mAb. (Cytokeratin 19 antibody (AA 80-400))

IHC

Western blot analysis using anti-KRT19 monoclonal antibody against truncated KRT19-His recombinant protein (1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2). (Cytokeratin 19 antibody (AA 80-400))

2 images

(2 references)

Catalog No. ABIN969076

Datasheet as PDF

Target See all Cytokeratin 19 (KRT19) Antibodies

Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
Binding Specificity
21

16

16

11

8

8

6

5

5

5

5

5

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 80-400
Reactivity
267

95

76

7

7

6

5

5

4

2

2

2

2

2

2

1

1

1

1

1
Human
Host
142

132

3

2

1
Mouse
Compatible Secondaries
Clonality
141

139
Monoclonal
Conjugate
123

32

20

13

7

5

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

1

1
This Cytokeratin 19 antibody is un-conjugated
Application
192

94

85

80

68

45

41

39

33

31

22

22

7

6

6

5

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification

purified

Immunogen

Purified recombinant fragment of Cytokeratin 19 (aa80-400) expressed in E. coli.

Clone

9H8G6

Isotype

IgG1

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Application Notes

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Flanagan, Pineda, Knapp, De Las Morenas, Lee, Braverman: "Expression of cytokeratin 19 in the diagnosis of thyroid papillary carcinoma by quantitative polymerase chain reaction." in: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Vol. 14, Issue 2, pp. 168-74, (2008) (PubMed).

Mizuguchi, Nishiyama, Iwata, Nishida, Izumi, Tsukioka, Inoue, Uenishi, Wakasa, Suehiro: "Serum Sialyl Lewis x and cytokeratin 19 fragment as predictive factors for recurrence in patients with stage I non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 58, Issue 3, pp. 369-75, (2007) (PubMed).
Target

Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Alternative Name

Cytokeratin 19 (KRT19 Products)

Synonyms

CK19 antibody, K19 antibody, K1CS antibody, AI663979 antibody, EndoC antibody, Krt-1.19 antibody, Krt1-19 antibody, Ka19 antibody, k19 antibody, ck19 antibody, k1cs antibody, krt9 antibody, krt15 antibody, MGC76282 antibody, GK-19 antibody, MGC83069 antibody, KRT19 antibody, keratin 19 antibody, keratin 19 L homeolog antibody, keratin, type I cytoskeletal 19 antibody, KRT19 antibody, Krt19 antibody, krt19 antibody, krt19.L antibody, LOC100344434 antibody, LOC101117946 antibody

Background

Description: Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.
Aliases: CK19, K1CS, MGC15366, KRT19

Molecular Weight

44 kDa

Gene ID

3880

HGNC

3880