pan Keratin antibody

Catalog No. ABIN969074

Product Details anti-pan Keratin Antibody

Target: pan Keratin (panKRT)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This pan Keratin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purpose: Cytokeratin (Pan) Antibody

Characteristics: Pan

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of CK5 expressed in E. Coli.

Clone: 7H8C4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-pan Keratin antibody (ABIN969074)

Somjen, Katzburg, Posner, Livne, Kaye: "Systemic treatments with the low-calcemic 1,25(OH)(2)D(3) analogs JKF or QW increase both the morphological and biochemical responses to estradiol-17beta in rat tibiae." in: Journal of cellular biochemistry, Vol. 100, Issue 6, pp. 1406-14, (2007) (PubMed).

Scope, Schwendenwein, Frommlet: "Biological variation, individuality and critical differences of eight biochemical blood constituents in budgerigars (Melopsittacus undulatus)." in: The Veterinary record, Vol. 159, Issue 25, pp. 839-43, (2006) (PubMed).

Target Details for pan Keratin

Target: pan Keratin (panKRT)

Alternative Name: Cytokeratin (Pan) (panKRT Products)

Synonyms: xk70a antibody, keratin antibody, keratin S homeolog antibody, LOC431321 antibody, krt.S antibody

Background:

Description: Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors.

Aliases: K5, DDD, EBS2, KRT5A, KRT5

Gene ID: 3852

HGNC: 3852

UniProt: P13647