CLOCK antibody

Catalog No. ABIN969059

Product Details anti-CLOCK Antibody

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLOCK antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Purpose: CLOCK Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CLOCK expressed in E. Coli.

Clone: 8F7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CLOCK antibody (ABIN969059)

Kuo, Chen, Yeh, Hou, Chang, Hsu, Chang: "Disturbance of circadian gene expression in breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 4, pp. 467-74, (2009) (PubMed).

Lee, Paik, Kang, Lim, Kim: "Allelic variants interaction of CLOCK gene and G-protein beta3 subunit gene with diurnal preference." in: Chronobiology international, Vol. 24, Issue 4, pp. 589-97, (2007) (PubMed).

Target Details for CLOCK

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Alternative Name: CLOCK (CLOCK Products)

Synonyms: CG7391 antibody, CLK antibody, CLOCK antibody, Dmel\\CG7391 antibody, Jerk antibody, Jrk antibody, PAS1 antibody, bHLHe10 antibody, clk antibody, clock antibody, dCLK antibody, dCLK/JRK antibody, dCLOCK antibody, dClck antibody, dClk antibody, dClock antibody, dclk antibody, jrk antibody, Xclk antibody, XClock antibody, zCLOCK1 antibody, zfCLOCK1 antibody, 5330400M04Rik antibody, KAT13D antibody, bHLHe8 antibody, mKIAA0334 antibody, Clock antibody, clock circadian regulator antibody, clock homolog (mouse) antibody, clock circadian regulator a antibody, circadian locomotor output cycles kaput antibody, clock circadian regulator L homeolog antibody, Clk antibody, CLOCK antibody, clock antibody, clocka antibody, Clock antibody, clock.L antibody

Background:

Description: This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.

Aliases: KAT13D, bHLHe8, KIAA0334, CLOCK

Molecular Weight: 95kDa

Gene ID: 9575

HGNC: 9575

UniProt: O15516

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism