CEBPB antibody

Catalog No. ABIN969049

Product Details anti-CEBPB Antibody

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CEBPB Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CEBPB expressed in E. Coli.

Clone: 3H9

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CEBPB antibody (ABIN969049)

Cappello, Zwergal, Kanclerski, Haas, Kandemir, Huber, Page, Brand: "C/EBPbeta enhances NF-kappaB-associated signalling by reducing the level of IkappaB-alpha." in: Cellular signalling, Vol. 21, Issue 12, pp. 1918-24, (2009) (PubMed).

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: CEBPB (CEBPB Products)

Background:

Description: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

Aliases: LAP, CRP2, TCF5, IL6DBP, NF-IL6, MGC32080, C/EBP-beta

Molecular Weight: 36kDa

Gene ID: 1051

HGNC: 1051

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation