CEBPA antibody

Catalog No. ABIN969048

Product Details anti-CEBPA Antibody

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: CEBPA Antibody

Sequence: RKSRDKAKRN VETKV

Purification: Ascitic fluid

Immunogen: Synthesized peptide of human CEBPA (AA: C-RKSRDKAKRNVETKV).

Clone: 5B7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CEBPA antibody (ABIN969048)

Jin, Zhang, Yan, Liu, Wang, Ge, Zhai: "C/EBPalpha regulates SIRT1 expression during adipogenesis." in: Cell research, Vol. 20, Issue 4, pp. 470-9, (2010) (PubMed).

Target Details for CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Alternative Name: CEBPA (CEBPA Products)

Synonyms: C/EBP-alpha antibody, CEBP antibody, C/ebpalpha antibody, CBF-A antibody, Cebp antibody, DBPCEP antibody, c/ebpa antibody, cb1062 antibody, wu:fj20f03 antibody, C/EBP antibody, C/EBPalpha antibody, xC/EBP antibody, cC/EBP antibody, C/EBP alpha antibody, CCAAT/enhancer binding protein alpha antibody, CCAAT/enhancer binding protein (C/EBP), alpha antibody, CCAAT/enhancer binding protein alpha L homeolog antibody, CEBPA antibody, Cebpa antibody, cebpa antibody, cebpa.L antibody

Background:

Description: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Aliases: CEBP, C/EBP-alpha

Molecular Weight: 42kDa

Gene ID: 1050

HGNC: 1050

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation