CEA antibody

Catalog No. ABIN969046

Product Details anti-CEA Antibody

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human CEA expressed in E. coli.

Clone: 3G12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-CEA antibody (ABIN969046)

Bjerner, Høgetveit, Wold Akselberg, Vangsnes, Paus, Bjøro, Børmer, Nustad: "Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study." in: Scandinavian journal of clinical and laboratory investigation, Vol. 68, Issue 8, pp. 703-13, (2008) (PubMed).

Huang, Wang, Yang, Yin, Geng, Li: "[Clinical value of combined determination of serum and pleural effusion level of CEA,CYFRA21-1, TPS in the diagnosis of lung cancer]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 24, Issue 4, pp. 370-2, (2008) (PubMed).

Target Details for CEA

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Alternative Name: CEA (CEA Products)

Synonyms: RGD1311281 antibody, carcinoembryonic antigen-related cell adhesion molecule 20 antibody, carcinoembryonic antigen gene family antibody, Ceacam20 antibody, Cea antibody

Background:

Description: Carcino Embryonic Antigen (CEA) is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). The carcinoembryonic antigen (CEA) is a member of a large family of glycoproteins and a useful tumor marker for adenocarcinoma. Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

Aliases: CEA, CD66e, DKFZp781M2392, CEACAM5

Molecular Weight: 77 kDa

Gene ID: 1048

HGNC: 1048