CA1 antibody (AA 25-90)

Catalog No. ABIN968998

Product Details anti-CA1 Antibody

Target: CA1 (Carbonic Anhydrase I (CA1))

Binding Specificity: AA 25-90

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA1 antibody is un-conjugated

Application: ELISA

Purpose: CA1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of CA1 (aa25-90) expressed in E. Coli.

Clone: 9D6D7

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CA1 antibody (ABIN968998)

Norwood: "Incidence of female androgenetic alopecia (female pattern alopecia)." in: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], Vol. 27, Issue 1, pp. 53-4, (2001) (PubMed).

Puscas, Coltau, Baican, Pasca, Domuta, Hecht: "Vasoconstrictive drugs increase carbonic anhydrase I in vascular smooth muscle while vasodilating drugs reduce the activity of this isozyme by a direct mechanism of action." in: Drugs under experimental and clinical research, Vol. 27, Issue 2, pp. 53-60, (2001) (PubMed).

Target Details for CA1

Target: CA1 (Carbonic Anhydrase I (CA1))

Alternative Name: CA1 (CA1 Products)

Background:

Description: CA1: carbonic anhydrase I. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.

Aliases: Car1, CA1

Gene ID: 759

HGNC: 759

UniProt: P00915