ATM antibody
(1 reference)-
- Target See all ATM Antibodies
- ATM (Ataxia Telangiectasia Mutated (ATM))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ATM antibody is un-conjugated
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Application
- ELISA
- Purpose
- ATM Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human ATM expressed in E. Coli.
- Clone
- 5C5
- Isotype
- IgG1
- Top Product
- Discover our top product ATM Primary Antibody
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anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody
ATM Reactivity: Human WB, IHC, ELISA, IP, IF, FACS, FM Host: Mouse Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM Reactivity: Human WB, IHC, ELISA, IP, IF, FACS, FM Host: Mouse Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (C-Term) antibodyATM Reactivity: Human, Mouse WB, IHC, ELISA, IP, IF, FACS, ICC Host: Rabbit Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2484-2748) antibodyATM Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2681-2750) antibodyATM Reactivity: Human, Mouse WB, ELISA, IHC (p), IF (p), IF (cc), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM Reactivity: Human WB, IHC, ELISA, IP Host: Rabbit Monoclonal 4E11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody (HRP)ATM Reactivity: Human WB, IHC, ELISA, FM Host: Mouse Monoclonal 10H11-E12 HRP
anti-Ataxia Telangiectasia Mutated (ATM) (AA 486-742) antibodyATM Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM Reactivity: Human IHC, ELISA, FACS Host: Rabbit Monoclonal 3G11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibodyATM Reactivity: Human IF, DB Host: Rabbit Polyclonal RB8121 unconjugated
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs." in: American journal of human genetics, Vol. 83, Issue 2, pp. 243-53, (2008) (PubMed).
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: "ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs." in: American journal of human genetics, Vol. 83, Issue 2, pp. 243-53, (2008) (PubMed).
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- Target
- ATM (Ataxia Telangiectasia Mutated (ATM))
- Alternative Name
- ATM (ATM Products)
- Background
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Description: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.Tissue specificity: Found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes.
Aliases: AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, DKFZp781A0353, ATM
- Molecular Weight
- 351kDa
- Gene ID
- 472
- HGNC
- 472
- UniProt
- Q13315
- Pathways
- p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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