APOO antibody

Catalog No. ABIN968964

Product Details anti-APOO Antibody

Target: APOO (Apolipoprotein O (APOO))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purpose: ApoO Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of ApoO expressed in E. Coli.

Clone: 2F1

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-APOO antibody (ABIN968964)

Lamant, Smih, Harmancey, Philip-Couderc, Pathak, Roncalli, Galinier, Collet, Massabuau, Senard, Rouet: "ApoO, a novel apolipoprotein, is an original glycoprotein up-regulated by diabetes in human heart." in: The Journal of biological chemistry, Vol. 281, Issue 47, pp. 36289-302, (2006) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Target Details for APOO

Target: APOO (Apolipoprotein O (APOO))

Alternative Name: ApoO (APOO Products)

Background:

Description: ApoO: apolipoprotein O, also known as MYO25, FAM121B, MGC4825. Entrez Protein NP_077027. It is a chrondroitin-sulfate chain containing member of the apolipoprotein family and is an original glycoprotein up-regulated by diabetes in human Heart. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.

Aliases: MYO25, FAM121B, MGC4825

Molecular Weight: 22.2kDa

Gene ID: 79135

HGNC: 79135

UniProt: Q9BUR5