AAT antibody
-
- Target
- AAT
- Reactivity
- Human, Mouse
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human AAT expressed in E. coli.
- Clone
- 2B12
- Isotype
- IgG1
-
-
- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
-
-
Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients." in: Neuro endocrinology letters, Vol. 29, Issue 4, pp. 482-4, (2008) (PubMed).
: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, (2005) (PubMed).
: "
-
Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients." in: Neuro endocrinology letters, Vol. 29, Issue 4, pp. 482-4, (2008) (PubMed).
-
- Target
- AAT
- Synonyms
- A1A antibody, A1AT antibody, AAT antibody, PI antibody, PI1 antibody, PRO2275 antibody, alpha1AT antibody, serpin family A member 1 antibody, SERPINA1 antibody
- Background
-
Description: AAT, also known as SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
Aliases: PI, A1A, AAT, PI1, A1AT, SERPINA1
- Molecular Weight
- 47 kDa
- Gene ID
- 5265
- HGNC
- 5265
-