GSTP1 antibody (AA 5-210)

Catalog No. ABIN968135

Product Details anti-GSTP1 Antibody

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Binding Specificity: AA 5-210

Reactivity: Human, Mouse, Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSTP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine)

Characteristics: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human GST-pi aa. 5-210

Clone: 3-GST

Isotype: IgG1

Application Details

Comment:

Related Products: ABIN967389, ABIN968535

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store undiluted at -20° C.

References for anti-GSTP1 antibody (ABIN968135)

Ali-Osman, Akande, Antoun, Mao, Buolamwini: "Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10004-12, (1997) (PubMed).

Zhou, Evans, London, Xia, Zou, Shen, Clapper: "Glutathione S-transferase expression in hepatitis B virus-associated human hepatocellular carcinogenesis." in: Cancer research, Vol. 57, Issue 13, pp. 2749-53, (1997) (PubMed).

Kano, Sakai, Muramatsu: "Structure and expression of a human class pi glutathione S-transferase messenger RNA." in: Cancer research, Vol. 47, Issue 21, pp. 5626-30, (1987) (PubMed).

Target Details for GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Alternative Name: GST-pi (GSTP1 Products)

Synonyms: DFN7 antibody, FAEES3 antibody, GST3 antibody, GSTP antibody, PI antibody, GST-P antibody, Gst3 antibody, Gstp antibody, Gstp2 antibody, gst-Pi antibody, GstpiB antibody, glutathione S-transferase P-like antibody, glutathione S-transferase pi 1 antibody, glutathione S-transferase pi 1 L homeolog antibody, glutathione S-transferase, pi 1 antibody, LOC100739163 antibody, GSTP1 antibody, Gstp1 antibody, LOC100861197 antibody, gstp1.L antibody

Background: Glutathione-S-Transferases (GSTs) are a family of dimeric proteins that catalyze the S-conjugation of glutathione with many compounds for detoxification. The GSTs are categorized into four classes based on their biochemical and structural properties: alpha, µ, pi, and theta. GST-pi is of particular interest because it is over-expressed in many tumors, but is either absent or expressed at low levels in the corresponding normal tissues. This high expression of GST-pi is associated with malignant transformation and correlates with a decrease in GST activity. Three different GST-pi proteins have been isolated and designated as hGSTP1A, hGSTP1B, and hGSTP1C. These isoforms are nearly identical, varying by only one to two amino acids. This antibody is routinely tested by western blot analysis.
Synonyms: Glutathione-S-Transferase-pi

Molecular Weight: 23 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin