HSPA4 antibody (AA 703-858)

Catalog No. ABIN968011

Product Details anti-HSPA4 Antibody

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Binding Specificity: AA 703-858

Reactivity: Human, Mouse, Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSPA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Cross-Reactivity: Rat (Rattus), Human, Mouse (Murine), Dog (Canine)

Characteristics: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Hamster Hsp110 aa. 703-858

Clone: 21-Hsp110

Isotype: IgG1

Application Details

Comment:

Related Products: ABIN968545, ABIN967389

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store undiluted at -20° C.

References for anti-HSPA4 antibody (ABIN968011)

Moore, Scheinman, Bellgrau: "The identification of a novel T cell activation state controlled by a diabetogenic gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 241-8, (2001) (PubMed).

Lee-Yoon, Easton, Murawski, Burd, Subjeck: "Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15725-33, (1995) (PubMed).

Target Details for HSPA4

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Alternative Name: Hsp110 (HSPA4 Products)

Background: With the exception of Hsp110, the stress or heat shock proteins have been thoroughly characterized. Hsp110 has been reported to be expressed in most tissues. Like other stress proteins, Hsp110 is induced by heat shock and its induction is associated with thermotolerance. The sequence of Hsp110 reportedly bears similarity to several Hsp70-related proteins that have been termed Hsp110/SSE. The carboxy-terminal domains of these proteins and Hsp110 contain a putative peptide-binding site. These proteins also contain six highly conserved regions found in the same progression, as well as five conserved ATP-binding motifs. This antibody is routinely tested by western blot analysis.
Synonyms: Heat Shock Protein-110

Molecular Weight: 110 kDa