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Cadherin 4 antibody (AA 22-201)

CDH4 Reactivity: Mouse, Rat WB, IHC, IP Host: Mouse Monoclonal 48-R unconjugated
Catalog No. ABIN967954
  • Target See all Cadherin 4 (CDH4) Antibodies
    Cadherin 4 (CDH4)
    Binding Specificity
    • 15
    • 10
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-201
    Reactivity
    • 64
    • 22
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 59
    • 5
    • 1
    Mouse
    Clonality
    • 61
    • 4
    Monoclonal
    Conjugate
    • 26
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cadherin 4 antibody is un-conjugated
    Application
    • 53
    • 25
    • 21
    • 20
    • 14
    • 13
    • 13
    • 10
    • 9
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Cross-Reactivity
    Rat (Rattus)
    Characteristics
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse R-Cadherin aa. 22-201
    Clone
    48-R
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CDH4 Primary Antibody
  • Comment

    Related Products: ABIN968545, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store undiluted at -20°C.
  • Tanihara, Sano, Heimark, St John, Suzuki: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).

    Hutton, Christofori, Chi, Edman, Guest, Hanahan, Kelly: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).

    Matsunami, Miyatani, Inoue, Copeland, Gilbert, Jenkins, Takeichi: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).

  • Target
    Cadherin 4 (CDH4)
    Alternative Name
    R-Cadherin (CDH4 Products)
    Synonyms
    cad4 antibody, rcad antibody, R-cadherin antibody, cadherin-4 antibody, AW120700 antibody, R-Cadh antibody, Rcad antibody, Cdh4l antibody, zgc:136316 antibody, CAD4 antibody, RCAD antibody, cadherin 4 antibody, cadherin 4, type 1, R-cadherin (retinal) antibody, Cadherin-4 antibody, cdh4 antibody, Cdh4 antibody, CDH4 antibody, cdh-4 antibody
    Background
    R-Cadherin was first isolated from chicken retina, but was subsequently shown to be present and highly conserved in a variety of tissues from several different species. A 913 amino acid polypeptide, R-Cadherin is highly homologous to Cadherin-4, but is most closely related to another family member, N-Cadherin. In experiments using chimeric L cells expressing chicken or mouse Cadherins, those cells expressing mouse or chicken R-Cadherin were able to aggregate with each other as well as with cells expressing N-Cadherin. However, there was no aggregation of R-Cadherin expressing cells, with P- or E-Cadherin expressing cells. This suggests that the roles of specific cadherins are conserved among types in the determination of heterogenous cell segregation and distribution during tissue morphogenesis and maintenance.
    Molecular Weight
    100 kDa
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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