Transferrin Receptor antibody
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- Target See all Transferrin Receptor (TFRC) Antibodies
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Transferrin Receptor antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. The specificity of these antibodies, as demonstrated by immunoprecipitation, are equivalent to OKT9, B3/25 and BerT9.
- Purification
- Purified.
- Immunogen
- Cell line KG1.
- Clone
- B349(DF1513)
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TFRC Primary Antibody
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- Application Notes
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Immunofluorescense 10-20 micrograms/ml.
Flow cytometry: 1 micrograms/10^6 cells.
Immunohistochemistry: (Acetone-fixed frozen) 5-15 micrograms/mL using avidin-biotin system. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.
Staining Procedure: This antibody can be used on frozen tissue sections only in IHC. - Comment
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Cellular Localization: Cell membrane.
Recommended Positive Control: Tonsil - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.4 mg/ml.
- Buffer
- 0.2 mg Immunoglobulin in cell culture supernatant, 50 mM Sodium Borate, 150 mM Sodium Chloride, pH 8.0
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).
: "Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization." in: The Journal of cell biology, Vol. 110, Issue 2, pp. 283-94, (1990) (PubMed).
: "
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Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Alternative Name
- Transferrin Receptor,CD71 (TFRC Products)
- Synonyms
- Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody
- Molecular Weight
- ~9095 kDa
- Gene ID
- 7037
- Pathways
- Transition Metal Ion Homeostasis
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