Rabbit IgG polyclonal antibody for BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 ( TNFAIP1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminal of human TNFalphaIP1, identical to the related rat and mouse sequence.< br/>Immunogen was affinity purified.
At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
He, Tan, Downey, So: "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 21, pp. 11979-84, (2001) (PubMed).
Wolf, Marks, Sarma, Byers, Katz, Shows, Dixit: "Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene." in: The Journal of biological chemistry, Vol. 267, Issue 2, pp. 1317-26, (1992) (PubMed).
Target
TNFAIP1
(Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))
Alternative Name
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2(hBACURD2) (TNFAIP1 Products)
Tumor necrosis factor, alpha-induced protein 1 (endothelial), also known as TNFAIP1, is a human gene. The gene, present in single copy, was located in the 17q22-q23 region. ssThis gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. The protein is involved in the primary response of the endothelium to TNF.