TDGF1
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
Western Bloting: 1/500 - 1/2000. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Format
Liquid
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Yang, Ghiotto, Barbarat, Olive: "The role of Tec protein-tyrosine kinase in T cell signaling." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 607-17, (1999) (PubMed).
TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. Synonyms: CR, CRGF, CRIPTO, TDGF1