Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of Baker's Yeast (Saccharomyces cerevisiae) TAF2 (Transcription initiation factor TFIID subunit 2, or TBP-associated factor 2)
TAF2
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Restrictions
For Research Use only
Storage
4 °C
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Leurent, Sanders, Ruhlmann, Mallouh, Weil, Kirschner, Tora, Schultz: "Mapping histone fold TAFs within yeast TFIID." in: The EMBO journal, Vol. 21, Issue 13, pp. 3424-33, (2002) (PubMed).
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Poon, Bai, Campbell, Bjorklund, Kim, Zhou, Kornberg, Weil: "Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 18, pp. 8224-8, (1995) (PubMed).
Jacquet, Buhler, Iborra, Francingues-Gaillard, Soustelle: "The MAT locus revisited within a 9.8 kb fragment of chromosome III containing BUD5 and two new open reading frames." in: Yeast (Chichester, England), Vol. 7, Issue 8, pp. 881-8, (1992) (PubMed).
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Target
TAF2
(TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))
TAF2 (Transcription initiation factor TFIID subunit 2, or TBP-associated factor 2) functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. The 1.2 MDa TFIID complex is composed of TATA binding protein (TBP) and the 14 TBP-associated factors. Synonyms: TAF150(BP-associated factor 150 kDa), TSM1, YCR42C, YCR724