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SCD antibody
SCD
Reactivity: Human, Mouse
WB, ELISA, IHC, IP
Monoclonal
unconjugated
Product Details anti-SCD Antibody
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Target
See all SCD Antibodies
SCD
(Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
Reactivity
All reactivities for SCD antibodies
Human, Mouse
Host
Please inquire
Clonality
All clonalities for SCD antibodies
Monoclonal
Conjugate
All conjugates for SCD antibodies
This SCD antibody is un-conjugated
Application
All applications for SCD antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
Specificity
Full length recombinant protein. Reacts with human and mouse proteins.
Isotype
IgG2b
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Discover our top product SCD Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot, ELISA, IP, and IHC in obesity research.
Restrictions
For Research Use only
Handling
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Concentration
1mg/ml
Buffer
PBS, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for SCD
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Target
SCD
(Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
Alternative Name
SCD1 (SCD Products )
Synonyms
FADS5 antibody, MSTP008 antibody, SCD1 antibody, SCDOS antibody, AA589638 antibody, AI265570 antibody, Scd antibody, Scd-1 antibody, ab antibody, SCD antibody, fads5 antibody, scd1 antibody, scdos antibody, F27J15.17 antibody, F27J15_17 antibody, STOMATAL CYTOKINESIS-DEFECTIVE 1 antibody, cds2 antibody, desaturase antibody, stearoyl-CoA desaturase antibody, acyl-CoA desaturase antibody, Acyl-CoA desaturase antibody, stearoyl-Coenzyme A desaturase 1 antibody, stearoyl-CoA desaturase (delta-9-desaturase) antibody, stearoyl-CoA desaturase (delta-9-desaturase) S homeolog antibody, stomatal cytokinesis defective / SCD1 protein (SCD1) antibody, acyl-CoA desaturase-like antibody, SCD antibody, CIMG_08158 antibody, VIBHAR_RS23280 antibody, acod antibody, Scd1 antibody, Scd antibody, scd antibody, LOC100346561 antibody, scd.S antibody, SCD1 antibody, LOC100719661 antibody, LOC101835884 antibody, LOC109101093 antibody
Background
Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.
Gene ID
20249
Pathways
Brown Fat Cell Differentiation
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