Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Fruit Fly (Drosophila melanogaster) PSF1 protein
GINS1
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Restrictions
For Research Use only
Storage
4 °C
Hoskins, Carlson, Kennedy, Acevedo, Evans-Holm, Frise, Wan, Park, Mendez-Lago, Rossi, Villasante, Dimitri, Karpen, Celniker: "Sequence finishing and mapping of Drosophila melanogaster heterochromatin." in: Science (New York, N.Y.), Vol. 316, Issue 5831, pp. 1625-8, (2007) (PubMed).
Smith, Shu, Mungall, Karpen: "The Release 5.1 annotation of Drosophila melanogaster heterochromatin." in: Science (New York, N.Y.), Vol. 316, Issue 5831, pp. 1586-91, (2007) (PubMed).
Quesneville, Bergman, Andrieu, Autard, Nouaud, Ashburner, Anxolabehere: "Combined evidence annotation of transposable elements in genome sequences." in: PLoS computational biology, Vol. 1, Issue 2, pp. 166-75, (2005) (PubMed).
Kaminker, Bergman, Kronmiller, Carlson, Svirskas, Patel, Frise, Wheeler, Lewis, Rubin, Ashburner, Celniker: "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective." in: Genome biology, Vol. 3, Issue 12, pp. RESEARCH0084, (2003) (PubMed).
Misra, Crosby, Mungall, Matthews, Campbell, Hradecky, Huang, Kaminker, Millburn, Prochnik, Smith, Tupy, Whitfied, Bayraktaroglu, Berman, Bettencourt, Celniker, de Grey, Drysdale, Harris, Richter, Russo, Schroeder, Shu, Stapleton, Yamada, Ashburner, Gelbar: "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." in: Genome biology, Vol. 3, Issue 12, pp. RESEARCH0083, (2003) (PubMed).
PSF1 is an evolutionarily conserved DNA replication factor, which forms the GINS complex with PSF2, PSF3, and SLD5. The tetrameric GINS complex plays an essential role in the initiation and elongation steps of eukaryotic DNA replication. GINS may function in a pathway that involves Cdc45 and is necessary for DNA polymerase epsilon chromatin binding.