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- Target See all p53 (TP53) Antibodies
- p53 (TP53) (Tumor Protein P53 (TP53))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This p53 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- P53 (Ab-315) antibody detects endogenous levels of total p53 protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
- Top Product
- Discover our top product TP53 Primary Antibody
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- Application Notes
- WB: 1:500~1:1000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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Site-specific phosphorylation of human p53 protein determined by mass spectrometry." in: Biochemistry, Vol. 40, Issue 13, pp. 4053-66, (2001) (PubMed).
: "The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5923-34, (1997) (PubMed).
: "Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes." in: Oncogene, Vol. 13, Issue 12, pp. 2527-39, (1997) (PubMed).
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Site-specific phosphorylation of human p53 protein determined by mass spectrometry." in: Biochemistry, Vol. 40, Issue 13, pp. 4053-66, (2001) (PubMed).
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Alternative Name
- P53 (TP53 Products)
- Pathways
- p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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