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NOX3 antibody (C-Term)

NOX3 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966688
  • Target See all NOX3 Antibodies
    NOX3 (NADPH Oxidase 3 (NOX3))
    Binding Specificity
    • 15
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 44
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOX3 antibody is un-conjugated
    Application
    • 35
    • 24
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human NOX3(NADPH oxidase 3)
    Top Product
    Discover our top product NOX3 Primary Antibody
  • Restrictions
    For Research Use only
  • Storage
    4 °C
  • Ueno, Takeya, Miyano, Kikuchi, Sumimoto: "The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators." in: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23328-39, (2005) (PubMed).

    Cheng, Ritsick, Lambeth: "Nox3 regulation by NOXO1, p47phox, and p67phox." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34250-5, (2004) (PubMed).

    Cheng, Cao, Xu, van Meir, Lambeth: "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5." in: Gene, Vol. 269, Issue 1-2, pp. 131-40, (2001) (PubMed).

  • Target
    NOX3 (NADPH Oxidase 3 (NOX3))
    Alternative Name
    NOX3 (NOX3 Products)
    Synonyms
    GP91-3 antibody, het antibody, nmf250 antibody, MOX-2 antibody, NADPH oxidase 3 antibody, Nox3 antibody, NOX3 antibody, nox3 antibody
    Background
    NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. NOX3(NADPH oxidase 3) plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. NOX3(NADPH oxidase 3) is activated by the ototoxic drug cisplatin and by NOXO1. NOX3 is cooperatively activated by NCF1 and NCF2 or NOXA1 in a phorbol 12-myristate 13-acetate (PMA)-dependent manner. It is inhibited by diphenyleneiodonium chloride and interacts with and stabilizes CYBA/p22phox. NOX3 is expressed in fetal kidney and to a lower extent in liver, lung and spleen.
    Synonyms: MOX2
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