MYEF2 antibody (C-Term)

Catalog No. ABIN966551

Product Details anti-MYEF2 Antibody

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYEF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human MEF2 (myocyte enhancer factor 2)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-MYEF2 antibody (ABIN966551)

Zhao, Geng, Ge, Wang, Zhang, Kang: "Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells." in: Molecular and cellular biochemistry, Vol. 322, Issue 1-2, pp. 171-8, (2009) (PubMed).

Vega, Salas, Milne, Carracedo, Ribas, Ruibal, de León, González-Hernández, Benítez, Carracedo: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, (2008) (PubMed).

Molkentin, Li, Olson: "Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17199-204, (1996) (PubMed).

Krainc, Haas, Ward, Lipton, Bruns, Leifer: "Assignment of human myocyte-specific enhancer binding factor 2C (hMEF2C) to human chromosome 5q14 and evidence that MEF2C is evolutionarily conserved." in: Genomics, Vol. 29, Issue 3, pp. 809-11, (1996) (PubMed).

Hobson, Krahe, Garcia, Siciliano, Funanage: "Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23." in: Genomics, Vol. 29, Issue 3, pp. 704-11, (1996) (PubMed).

McDermott, Cardoso, Yu, Andres, Leifer, Krainc, Lipton, Nadal-Ginard: "hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors." in: Molecular and cellular biology, Vol. 13, Issue 4, pp. 2564-77, (1993) (PubMed).

Target Details for MYEF2

Target: MYEF2 (Myelin Expression Factor 2 (MYEF2))

Alternative Name: MEF2 (MYEF2 Products)

Synonyms: MYEF2 antibody, mef-2 antibody, mst156 antibody, mstp156 antibody, hst18564 antibody, 9430071B01 antibody, mKIAA1341 antibody, zgc:123351 antibody, zgc:152722 antibody, HsT18564 antibody, MEF-2 antibody, MST156 antibody, MSTP156 antibody, myelin expression factor 2 antibody, myelin basic protein expression factor 2, repressor antibody, myelin expression factor 2 L homeolog antibody, MYEF2 antibody, myef2 antibody, CpipJ_CPIJ011705 antibody, Myef2 antibody, myef2.L antibody

Background: The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. A family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many muscle-specific genes. The MEF2 genes are members of the MADS gene family, a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNAbinding domain.