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LSD1 antibody
KDM1A
Reactivity: Human
WB, ELISA, IHC
Monoclonal
unconjugated
Product Details anti-LSD1 Antibody
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Target
See all LSD1 (KDM1A) Antibodies
LSD1 (KDM1A)
(Lysine (K)-Specific Demethylase 1A (KDM1A))
Reactivity
All reactivities for LSD1 antibodies
Human
Host
Please inquire
Clonality
All clonalities for LSD1 antibodies
Monoclonal
Conjugate
All conjugates for LSD1 antibodies
This LSD1 antibody is un-conjugated
Application
All applications for LSD1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Specificity
Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)
Purification
Crude Asites are purified by protein A affinity chromatography.
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Western Blot: 1: 500- 1: 2,000 IHC(P): 1: 500- 1: 2,000 IHC(F): 1: 500- 1: 2,000 ELISA: Propose dilution 1: 10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Storage
-20 °C
References for anti-LSD1 antibody (ABIN966497)
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Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle : "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. " in: Nature , Vol. 437 , Issue 7057 , pp. 436-9 , (2005 ) (PubMed ).
Target Details for LSD1
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Target
LSD1 (KDM1A)
(Lysine (K)-Specific Demethylase 1A (KDM1A))
Alternative Name
LSD1/AOF2 (KDM1A Products )
Synonyms
AOF2 antibody, BHC110 antibody, KDM1 antibody, LSD1 antibody, 1810043O07Rik antibody, AA408884 antibody, Aof2 antibody, D4Ertd478e antibody, Kdm1 antibody, Lsd1 antibody, mKIAA0601 antibody, DKFZp459N2450 antibody, RGD1562975 antibody, aof2 antibody, kdm1 antibody, wu:fb82e06 antibody, wu:fc51a02 antibody, wu:fj36a05 antibody, wu:fj66b06 antibody, KDM1A antibody, lsd1 antibody, xLSD1 antibody, AtLSD1 antibody, F9F13.30 antibody, F9F13_30 antibody, LESION SIMULATING DISEASE antibody, LESION SIMULATING DISEASE 1 antibody, lysine demethylase 1A antibody, lysine (K)-specific demethylase 1A antibody, lysine (K)-specific demethylase 1a antibody, LSD1 zinc finger family protein antibody, KDM1A antibody, Kdm1a antibody, kdm1a antibody, LSD1 antibody
Background
The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Gene ID
23028
Pathways
Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Negative Regulation of intrinsic apoptotic Signaling , Warburg Effect
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