H2-K2 antibody

Catalog No. ABIN966244

Product Details anti-H2-K2 Antibody

Target: H2-K2 (Histocompatibility 2, K Region Locus 2 (H2-K2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2-K2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of mouse H2-K1 (H-2 class I histocompatibility antigen, K-B alpha chain )

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-H2-K2 antibody (ABIN966244)

Wollscheid, Bausch-Fluck, Henderson, OBrien, Bibel, Schiess, Aebersold, Watts: "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins." in: Nature biotechnology, Vol. 27, Issue 4, pp. 378-86, (2009) (PubMed).

Weiss, Golden, Zakut, Mellor, Fahrner, Kvist, Flavell: "The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens." in: The EMBO journal, Vol. 2, Issue 3, pp. 453-62, (2002) (PubMed).

Kern, Teng, Smolyar, Liu, Liu, Hussey, Spoerl, Chang, Reinherz, Wang: "Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb." in: Immunity, Vol. 9, Issue 4, pp. 519-30, (1998) (PubMed).

Fremont, Matsumura, Stura, Peterson, Wilson: "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb." in: Science (New York, N.Y.), Vol. 257, Issue 5072, pp. 919-27, (1992) (PubMed).

Reyes, Schöld, Itakura, Wallace: "Isolation of a cDNA clone for the murine transplantation antigen H-2Kb." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 10, pp. 3270-4, (1982) (PubMed).

Uehara, Coligan, Nathenson: "Amino acid sequence of the carboxyl-terminal hydrophilic region of the H-2Kb MHC alloantigen. Completion of the entire primary structure of the H-2Kb molecule." in: Biochemistry, Vol. 20, Issue 21, pp. 5940-5, (1982) (PubMed).

Target Details for H2-K2

Target: H2-K2 (Histocompatibility 2, K Region Locus 2 (H2-K2))

Alternative Name: H2-K1 (H2-K2 Products)

Synonyms: EG630499 antibody, Gm7035 antibody, H-2K1 antibody, H-2K1K antibody, H-2K2 antibody, H2-K1 antibody, histocompatibility 2, K region locus 2 antibody, H2-K2 antibody

Background: H2-K1 (H-2 class I histocompatibility antigen, K-B alpha chain ) is involved in the presentation of foreign antigens to the immune system. H2-K1 is heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). H2-K1 is a single-pass type I membrane protein. H2-K1 contains 1 Ig-like C1-type (immunoglobulin-like) Domain and belongs to the MHC class I family.
Synonyms: H2-K