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C14orf1 antibody (N-Term)

The Rabbit Polyclonal anti-C14orf1 antibody has been validated for IHC. It is suitable to detect C14orf1 in samples from Human and Mouse. There is 1 publication available.
Catalog No. ABIN966089

Quick Overview for C14orf1 antibody (N-Term) (ABIN966089)

Target

C14orf1 (Chromosome 14 Open Reading Frame 1 (C14orf1))

Reactivity

  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 4
Rabbit

Clonality

  • 4
Polyclonal

Conjugate

  • 4
This C14orf1 antibody is un-conjugated

Application

  • 3
  • 3
  • 1
  • 1
Immunohistochemistry (IHC)
  • Binding Specificity

    • 2
    • 1
    • 1
    N-Term

    Purification

    Purified by antigen-specific affinity chromatography.

    Immunogen

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse ERG28(Probable ergosterol biosynthetic protein 28)
  • Application Notes

    ELISA, Western blotting: 1µg/ml for 2hrs.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    This antibody is stored in PBS, 50% glycerol

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C
  • Mo, Valachovic, Bard: "The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p)." in: Biochimica et biophysica acta, Vol. 1686, Issue 1-2, pp. 30-6, (2004) (PubMed).

  • Target

    C14orf1 (Chromosome 14 Open Reading Frame 1 (C14orf1))

    Alternative Name

    ERG28

    Background

    ERG28(Probable ergosterol biosynthetic protein 28) has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. ERG28 may also be responsible for facilitating their interaction. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum. ERG28 interacts with ERG25, ERG26 and ERG27. It also interacts with ERG1, ERG3, ERG5, ERG6 and ERG11.
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