C14orf1 antibody (N-Term)

Catalog No. ABIN966089

Product Details anti-C14orf1 Antibody

Target: C14orf1 (Chromosome 14 Open Reading Frame 1 (C14orf1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C14orf1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse ERG28(Probable ergosterol biosynthetic protein 28)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-C14orf1 antibody (ABIN966089)

Mo, Valachovic, Bard: "The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p)." in: Biochimica et biophysica acta, Vol. 1686, Issue 1-2, pp. 30-6, (2004) (PubMed).

Target Details for C14orf1

Target: C14orf1 (Chromosome 14 Open Reading Frame 1 (C14orf1))

Alternative Name: ERG28 (C14orf1 Products)

Synonyms: ERG28 antibody, NET51 antibody, homolog of yeast ergosterol28 antibody, T27I1.5 antibody, T27I1_5 antibody, C7H14orf1 antibody, ergosterol biosynthesis 28 homolog antibody, ergosterol biosynthetic protein 28 antibody, ergosterol biosynthesis protein antibody, ERG28 antibody, LOC781060 antibody, ANI_1_490024 antibody, AOR_1_898014 antibody

Background: ERG28(Probable ergosterol biosynthetic protein 28) has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. ERG28 may also be responsible for facilitating their interaction. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum. ERG28 interacts with ERG25, ERG26 and ERG27. It also interacts with ERG1, ERG3, ERG5, ERG6 and ERG11.