Daf-2 antibody (C-Term)
DAF2
Reactivity: C. elegans
IHC
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Daf-2 (DAF2) products
- Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
- Binding Specificity
- C-Term
- Reactivity
- C. elegans
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (IHC)
- Purification
- Purified by antigen-specific affinity chromatography.
- Immunogen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)
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- Application Notes
- ELISA, Western blotting: 1µg/ml for 2hrs.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- This antibody is stored in PBS, 50% glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
- Alternative Name
- Daf-2
- Synonyms
- AI323748 antibody, Cd55b antibody, Daf antibody, Daf-TM antibody, TM-DAF antibody, CD55 molecule, decay accelerating factor for complement B antibody, Insulin-like receptor subunit beta antibody, Cd55b antibody, daf-2 antibody
- Background
- The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.
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