CNGA3 antibody (C-Term)

Catalog No. ABIN965909

Product Details anti-CNGA3 Antibody

Target: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Binding Specificity: C-Term

Reactivity: Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNGA3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of chicken CNG3 (Cyclic nucleotide gated channel, ROD photoreceptor, alpha subunit)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CNGA3

Target: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Alternative Name: CNG3 (CNGA3 Products)

Synonyms: ACHM2 antibody, CCNC1 antibody, CCNCa antibody, CCNCalpha antibody, CNCG3 antibody, CNG3 antibody, CNGA3 antibody, cyclic nucleotide gated channel alpha 3 antibody, CNGA3 antibody, Cnga3 antibody

Background: Visual signal transduction is mediated by a Gprotein coupled cascade using cGMP as second messenger. CNG3 (Cyclic nucleotide gated channel, ROD photoreceptor, alpha subunit) can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. The protein belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains 1 cyclic nucleotide-binding domain.

Pathways: Phototransduction