Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human Cytidine deaminase (Cytidine aminohydrolase)
CDA
Reactivity: Human
WB
Host: Mouse
Monoclonal
1C1
unconjugated
Application Notes
ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions
For Research Use only
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Demontis, Terao, Brivio, Zanotta, Bruschi, Garattini: "Isolation and characterization of the gene coding for human cytidine deaminase." in: Biochimica et biophysica acta, Vol. 1443, Issue 3, pp. 323-33, (1999) (PubMed).
The Cytidine deaminase (Cytidine aminohydrolase) scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Growth inhibition of granulocyte-macrophage colony-forming cells by human cytidine deaminase requires the catalytic function of the protein. It is highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.It belongs to the cytidine and deoxycytidylate deaminase family.