CD8 alpha antibody
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- Target See all CD8 alpha (CD8A) Antibodies
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD8 alpha antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Acetone-fixed) (IHC (af))
- Specificity
- This antibody consists of a disufide-linked / hetrodimer with a mW of 30 kD or an / homodimer with a MW of 32 kD. The CD molecule binds to HLA class I molecule during interaction of CD 8+ T cells with antigenpresenting cells or with target cells. CD 8+T cells include most of the cytotoxic T cells.
- Characteristics
- This antibody is directed against alpha chain of CD8 molecule.
- Purification
- Purified.
- Clone
- B441 (143-44 )
- Isotype
- IgG kappa
- Top Product
- Discover our top product CD8A Primary Antibody
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- Application Notes
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Flow: not tested in our lab.
IHC (acetone-fixed frozen).
Staining Procedure: Acetone-fixed tissue sections at 1:50-1:100 Antibody - Comment
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Cellular Localization: Cell membrane.
Recommended Positive Control: Human peripheral lymphocytes, Human tonsil. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/0.5 ml.
- Buffer
- Protein A/G purified, 0.2 mg in 50 mM Borate, 150mM NaCl, 20 % Glycerol, pH 8.0
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Binding of HIV-2 envelope glycoprotein to CD8 molecules and related chemokine production." in: Immunology, Vol. 95, Issue 2, pp. 214-8, (1999) (PubMed).
: "Alternation of QRS morphology and effect of radiofrequency ablation in idiopathic ventricular tachycardia." in: Pacing and clinical electrophysiology : PACE, Vol. 18, Issue 1 Pt 1, pp. 18-27, (1995) (PubMed).
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Binding of HIV-2 envelope glycoprotein to CD8 molecules and related chemokine production." in: Immunology, Vol. 95, Issue 2, pp. 214-8, (1999) (PubMed).
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Alternative Name
- CD8a (CD8A Products)
- Synonyms
- cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
- Molecular Weight
- 32 kDa
- Gene ID
- 925
- Pathways
- TCR Signaling
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