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- Target See all CD4 Antibodies
- CD4
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Reactivity
- Human
- Host
- Please inquire
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Clonality
- Monoclonal
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Conjugate
- This CD4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- Ni-NTA purified recombinant human CD4 expressed in E. Coli strain BL21 (DE3).
- Purification
- Antibodies are purified by protein A affinity chromatography
- Isotype
- IgG1
- Top Product
- Discover our top product CD4 Primary Antibody
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- Application Notes
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Western Blot, IHC and ELISA. Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Storage
- -20 °C
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Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).
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Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).
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- Target
- CD4
- Alternative Name
- CD4 (CD4 Products)
- Synonyms
- cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
- Background
- The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells
- Gene ID
- 920
- Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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