CA8 antibody (N-Term)

Catalog No. ABIN965733

This anti-CA8 antibody is a Rabbit Polyclonal antibody detecting CA8 in IHC. Suitable for Human and Mouse. This Primary Antibody has been cited in 5+ publications.

Quick Overview for CA8 antibody (N-Term) (ABIN965733)

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA8 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CA8 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CA8(Carbonic anhydrase VIII)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-CA8 antibody (ABIN965733)

Hirota, Ando, Hamada, Mikoshiba: "Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1." in: The Biochemical journal, Vol. 372, Issue Pt 2, pp. 435-41, (2003) (PubMed).

Taniuchi, Nishimori, Takeuchi, Fujikawa-Adachi, Ohtsuki, Onishi: "Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain." in: Neuroscience, Vol. 112, Issue 1, pp. 93-9, (2002) (PubMed).

Bergenhem, Sait, Eddy, Shows, Tashian: "Assignment of the gene for human carbonic anhydrase VIII(CA8) to chromosome 8q11-->q12." in: Cytogenetics and cell genetics, Vol. 71, Issue 3, pp. 299-300, (1995) (PubMed).

Kelly, Nógrádi, Walker, Caddy, Peters, Carter: "Lurching, reeling, waddling and staggering in mice--is carbonic anhydrase (CA) VIII a candidate gene?" in: Biochemical Society transactions, Vol. 22, Issue 3, pp. 359S, (1995) (PubMed).

Skaggs, Bergenhem, Venta, Tashian: "The deduced amino acid sequence of human carbonic anhydrase-related protein (CARP) is 98% identical to the mouse homologue." in: Gene, Vol. 126, Issue 2, pp. 291-2, (1993) (PubMed).

Target Details for CA8

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Alternative Name: CA8

Background: CA8(Carbonic anhydrase VIII) was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, Carbonic anhydrase VIII lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The Carbonic anhydrase VIII continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Carbonic anhydrase VIII belongs to the eukaryotic-type carbonic anhydrase family.