ACER1 antibody (N-Term)

Catalog No. ABIN965597

Product Details anti-ACER1 Antibody

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ASAH3(N-acylsphingosine amidohydrolase 3) or CER1(alkaline ceramidase)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ACER1

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Alternative Name: ASAH3 (ACER1 Products)

Background: ASAH3(N-acylsphingosine amidohydrolase 3) or CER1(alkaline ceramidase) deacylates ceramide to generate sphingosine and a fatty acid. Ceramidases deacylate ceramides, important intermediates in the metabolic pathway of sphingolipids. CER1 is selectively expressed in skin and may have a role in regulating the levels of bioactive lipids ceramide and S1P, as well as complex sphingolipids.