ARL1 antibody (N-Term)

Catalog No. ABIN965592

Product Details anti-ARL1 Antibody

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-ARL1 antibody (ABIN965592)

Van Valkenburgh, Shern, Sharer, Zhu, Kahn: "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).

Hong, Lee, Patton, Lin, Moss, Vaughan: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." in: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, (1998) (PubMed).

Target Details for ARL1

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Alternative Name: ARL1 (ARL1 Products)

Synonyms: ARFL1 antibody, 2310008D22Rik antibody, AU019749 antibody, zgc:92883 antibody, 72CDd antibody, ARL1 antibody, ARL1_DROME antibody, Arf antibody, Arf72A antibody, BcDNA:GM20805 antibody, CG 6025 antibody, CG6025 antibody, Dmel\CG6025 antibody, P25160 antibody, arf72A antibody, arf[72A] antibody, arl antibody, arl1 antibody, dARL1p antibody, dArl1 antibody, l(3)72Ae antibody, l(3)72CDd antibody, arfl1 antibody, ADP ribosylation factor like GTPase 1 antibody, ADP-ribosylation factor like GTPase 1 antibody, ADP-ribosylation factor-like 1 antibody, ADP-ribosylation factor-like protein 1 antibody, ADP ribosylation factor-like 1 antibody, ADP ribosylation factor like GTPase 1 L homeolog antibody, ARL1 antibody, Arl1 antibody, arl-1 antibody, arl1 antibody, arl1.L antibody

Background: ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.