ALDH1L1 antibody (C-Term)

Catalog No. ABIN965537

Product Details anti-ALDH1L1 Antibody

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1L1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse ALDH1L1(Aldehyde dehydrogenase 1 family member L1)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-ALDH1L1 antibody (ABIN965537)

Krupenko, Wagner: "Aspartate 142 is involved in both hydrolase and dehydrogenase catalytic centers of 10-formyltetrahydrofolate dehydrogenase." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35777-84, (2000) (PubMed).

Case, Kaisaki, Steele: "Resolution of rat liver 10-formyltetrahydrofolate dehydrogenase/hydrolase activities." in: The Journal of biological chemistry, Vol. 263, Issue 21, pp. 10204-7, (1988) (PubMed).

Target Details for ALDH1L1

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Alternative Name: ALDH1L1 (ALDH1L1 Products)

Synonyms: 10-FTHFDH antibody, 10-fTHF antibody, FDH antibody, FTHFD antibody, Fthfd antibody, 1810048F20Rik antibody, Neut2 antibody, fthfd antibody, ALDH1L1 antibody, DKFZp469C068 antibody, aldehyde dehydrogenase 1 family member L1 antibody, aldehyde dehydrogenase 1 family, member L1 antibody, cytosolic 10-formyltetrahydrofolate dehydrogenase antibody, aldehyde dehydrogenase 1 family member L1 L homeolog antibody, ALDH1L1 antibody, Aldh1l1 antibody, aldh1l1 antibody, LOC476506 antibody, LOC100465263 antibody, aldh1l1.L antibody

Background: ALDH1L1 ((Aldehyde dehydrogenase 1 family member L1) converts 10-formyltetrahydrofolate, a precursor for nucleotide biosynthesis, to tetrahydrofolate. The protein comprises two functional domains: a hydrolase domain that removes a formyl group from 10-formyltetrahydrofolate and a NADP(+)-dependent dehydrogenase domain that reduces the formyl to carbon dioxide. It is localized in cytoplasm and contains 1 acyl carrier domain. In the N-terminal section, it belongs to the GART family. In the C-terminal section, it belongs to the aldehyde dehydrogenase family.