IL29 antibody

Catalog No. ABIN964763

Product Details anti-IL29 Antibody

Target: IL29 (Interleukin 29 (IL29))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL29 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: Anti-IL-29 is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human IL-29 protein. A BLAST analysis was used to suggest cross-reactivity with IL-29 from human sources based on 100% homology with the immunizing sequence. Based on high to 100% homology, there is a chance of cross-reactivity to IL-29 from a wide variety of animals. Cross-reactivity with IL-29 from other sources has not been determined.

Characteristics: IL-29 (Interleukin-29) is a secreted cytokine with immunomodulatory activity. It may play a role in antiviral immunity. It up-regulates MHC class I antigen expression. IL-29 is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Its induction is by viral infections or double stranded RNA. Anti-IL-29 antibody is ideal for investigators involved in Immunology research.

Purification: purified

Immunogen: This IgG fraction antibody was prepared from rabbit antiserum after repeated immunizations with mature length recombinant human IL-29 protein produced in E.coli.
Immunogen Type: RecombinantProtein

Isotype: IgG

Application Details

Application Notes: This purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 19.9 kDa in size corresponding to the mature human IL-29 protein by western blotting in appropriate cell lysate or extract.

Comment:

Gene Name: IL-29

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Without preservative

Storage: 4 °C/-20 °C

Storage Comment: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is six (6) months from date of opening.

Expiry Date: 6 months

Target Details for IL29

Target: IL29 (Interleukin 29 (IL29))

Alternative Name: IL-29 (IL29 Products)

Synonyms: IL-29 antibody, IL29 antibody, interferon lambda 1 antibody, interferon lambda-1 antibody, interleukin 29 (interferon, lambda 1) antibody, IFNL1 antibody, LOC612539 antibody, IL29 antibody

Background: IL-29 (Interleukin-29) is a secreted cytokine with immunomodulatory activity. It may play a role in antiviral immunity. It up-regulates MHC class I antigen expression. IL-29 is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Its induction is by viral infections or double stranded RNA. Anti-IL-29 antibody is ideal for investigators involved in Immunology research.
Synonyms: Interferon lambda-1, IFN-lambda-1 cytokine

Gene ID: 282618

NCBI Accession: NP_742152

UniProt: Q8IU54