CCL3L1 antibody
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- Target See all CCL3L1 Antibodies
- CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))
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Reactivity
- Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCL3L1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Supplier Product No.
- 200-401-b61
- Supplier
- Rockland
- Purpose
- CCL3L1 Antibody
- Cross-Reactivity (Details)
- This antibody is specific for swine CCL3L1 protein.
- Characteristics
- Synonyms: rabbit anti-CCL3L1 Antibody, CCL3L3, Chemokine (C-C motif) ligand 3-like 1, macrophage inflammatory protein 1 alpha, MIP-1 alpha, ld78beta, scya3l1, small inducible cytokine a3-like 1
- Purification
- This product was Protein-A purified from monospecific antiserum by chromatography.
- Immunogen
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Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to the 70 amino acids of the mature swine CCL3L1 protein.
Immunogen Type: Recombinant Protein
- Isotype
- IgG
- Top Product
- Discover our top product CCL3L1 Primary Antibody
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- Application Notes
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Application Note: This protein-A purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7.8 kDa in size corresponding to swine CCL3L1 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: User Optimized
Other: User Optimized
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
- Concentration
- 1.0 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Expiry Date
- 12 months
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- Target
- CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))
- Alternative Name
- CCL3L1 (CCL3L1 Products)
- Background
- Background: Chemokine (C-C motif) ligand 3-like 1 (CCL3L1), also known as macrophage inflammatory protein 1 alpha (MIP-1 alpha, other synonyms: ld78beta, scya3l1, small inducible cytokine a3-like 1), is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. In humans, CCL3L1 is encoded by a variable copy-number gene. The CC family induces MCP1 and RANTES, and exhibits a variety of proinflammatory activities including chemotaxis, and functional and proliferative activation of leukocytes, lymphocytes, and macrophages. Its signal is transmitted through transmembrane receptors, CC chemokine receptors, CCR1, CCR3 and CCR5. CCL3L1/MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils. CCL3L1 binds to several chemokine receptors. In humans these receptors include chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. In swine, CCL3L1 protein is 86 % similar to CCL4 protein, and 73 % similar to CCL5.
- Gene ID
- 494459, 57527998
- UniProt
- A1YM34
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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