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CDNF antibody

CDNF Reactivity: Human WB, ELISA Host: Mouse Monoclonal 7D6 unconjugated
Catalog No. ABIN956415
  • Target See all CDNF Antibodies
    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
    Reactivity
    • 30
    • 14
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 34
    • 6
    • 1
    • 1
    Mouse
    Clonality
    • 35
    • 7
    Monoclonal
    Conjugate
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDNF antibody is un-conjugated
    Application
    • 24
    • 16
    • 13
    • 13
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Human, CDNF protein
    Purification
    purified by protein G affinity chromatography
    Immunogen
    Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant
    Clone
    7D6
    Isotype
    IgG1
    Top Product
    Discover our top product CDNF Primary Antibody
  • Application Notes
    ELISA: 1:64 000, WB: 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
    Comment

    Synonym: ARMETL1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml
    Buffer
    PBS pH 7.4, with 0.1%
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.
    Storage
    -20 °C
    Storage Comment
    This product is shipped in non-frozen liquid form in ambient conditions
  • Galli, Lindholm, Kontturi, Saarma, Urtti, Yliperttula: "Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy." in: Cell transplantation, Vol. 28, Issue 4, pp. 413-424, (2020) (PubMed).

  • Target
    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
    Alternative Name
    CDNF (CDNF Products)
    Background
    CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta
    UniProt
    Q49AH0
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