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CDNF antibody

CDNF Reactivity: Human WB, ELISA Host: Mouse Monoclonal 7D6 unconjugated
Catalog No. ABIN956415
  • Target See all CDNF Antibodies
    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
    Reactivity
    • 29
    • 13
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 6
    • 1
    • 1
    Mouse
    Clonality
    • 34
    • 7
    Monoclonal
    Conjugate
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDNF antibody is un-conjugated
    Application
    • 24
    • 16
    • 13
    • 13
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Human, CDNF protein
    Purification
    purified by protein G affinity chromatography
    Immunogen
    Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant
    Clone
    7D6
    Isotype
    IgG1
    Top Product
    Discover our top product CDNF Primary Antibody
  • Application Notes
    ELISA: 1:64 000, WB: 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
    Comment

    Synonym: ARMETL1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml
    Buffer
    PBS pH 7.4, with 0.1%
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.
    Storage
    -20 °C
    Storage Comment
    This product is shipped in non-frozen liquid form in ambient conditions
  • Galli, Lindholm, Kontturi, Saarma, Urtti, Yliperttula: "Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy." in: Cell transplantation, Vol. 28, Issue 4, pp. 413-424, (2020) (PubMed).

  • Target
    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
    Alternative Name
    CDNF (CDNF Products)
    Synonyms
    ARMETL1 antibody, 9330140G23 antibody, Armetl1 antibody, cerebral dopamine neurotrophic factor antibody, CDNF antibody, Cdnf antibody
    Background
    CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta
    UniProt
    Q49AH0
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