CDNF antibody

Catalog No. ABIN956414

Product Details anti-CDNF Antibody

Target: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDNF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human, CDNF protein

Purification: CDNF-affinity purified

Immunogen: Recombinant human CDNF protein produced usingCHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Purifiedfrom cell culture supernatant. 

Isotype: IgG

Application Details

Application Notes: Westernimmunoblotting, recommended dilution 1:6 000 to 1:10 000, ELISA: 1:125 000

Comment:

Synonym: ARMETL1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml

Buffer: Concentrated ammonium sulphide in PBS pH 7.4

Handling Advice: As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use.

Storage: 4 °C

Storage Comment: This product is shipped in non-frozen liquid form in ambient conditions

Target Details for CDNF

Target: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Alternative Name: CDNF (CDNF Products)

Synonyms: ARMETL1 antibody, 9330140G23 antibody, Armetl1 antibody, cerebral dopamine neurotrophic factor antibody, CDNF antibody, Cdnf antibody

Background: CDNF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA- (Lindholmet al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration(Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’sdisease. When administered after 6-OHDA or MPTP –lesioning it restores thedopaminergic function and prevents degeneration of dopamine neurons insubstantia nigra pars compacta

UniProt: Q49AH0