Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
Characteristics
Concentration Definition: by Refractometry
Immunogen
BIVM peptide corresponding to a region near carboxy terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). Sequence information: C-R-N-S-G-Y-Q-G-Y-S-D-Y-D-G-N-D
BIVM
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 647
Application Notes
This polyclonal antibody reacts human BIVM at the C-terminal region and is useful for detection of BIVM by ELISA or western blotting. Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation. For immunoblotting a 57 kDa band corresponding to human BIVM is detected. Unstimulated HeLa cells can be used as a positive control.
Restrictions
For Research Use only
Format
Liquid
Concentration
90 mg/mL
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
BIVM (for basic, immunoglobulin-like variable motif-containing) refers to a recently identified gene product that maps to human chromosome 13q32-q33 and is predicted to encode a 503-amino acid protein. BIVM shows ubiquitous expression in normal human tissue and the presence of a 5' CpG island suggests it is a housekeeping gene. BIVM is likely essential for some aspect of basic cellular function. BIVM is highly charged and localizes to the cytoplasm and nucleus where it may bind to either DNA or RNA or associate with other cellular proteins. Significant sequence homology exists with many organisms. Synonyms: Basic immunoglobulin-like variable motif-containing protein BIVM